Eleonor Picas studied at the Porto Conservatory of Music. She studied harp at the Royal Conservatory of Music in Madrid, in the class of Professor Maria Rosa Calvo-Manzano, and completed her degree in harp at the University of Minho. She has also studied with Josef Molner, Lisetta Rossi, Erika Wadenburg, Jeuan Jones and Stephanie Manzo.

She regularly collaborates with the Orquestra das Beiras, with whom she has performed solo, and has worked with many others such as the Orquestra Gulbenkian and the Orquestra Nacional do Porto. She is the founder of the Trio Eire, which has pieces dedicated to it by composers such as Fernando Lapa and Vasco Negreiros. She is also a member of the Harawi Ensemble. In 2010, she took part in the premiere of a work by Sérgio Azevedo and Debussy's trio sonata. He is a member of the Space Ensemble, with whom he has performed all over the country. He recorded the disc "João" with jazz singer Maria João, with whom he performed concerts all over the country and in Spain. He has also recorded with Vai-de-Roda, Frei Fado D'El Rei, Zoe, Luísa Sobral, and several CDs with Bando dos Gambozinos, where he works.

She teaches harp at the Calouste Gulbenkian Conservatory of Music in Braga.